招生专业

海洋生物学，海洋化学

个人详细介绍

1. 教育经历

   2004.9—2008.7 中山大学,  材料化学,  本科,  学士学位

   2008.9—2011.7 厦门大学,  有机化学,  硕士研究生,  硕士学位，导师：黄培强 教授，叶剑良副教授

   2011.8—2015.9 荷兰代尔夫特理工大学 (Delft University of Technology),  生物催化,  博士研究    

                              生,  博士学位，导师：Prof. Ulf Hanefeld

2. 工作经历

    2018.10 - 至今  中山大学  海洋科学学院  副教授  硕士研究生导师

    2015.10-2018.10 中山大学 海洋科学学院 特聘副研究员

 

3.研究方向

海洋微生物催化与转化

 

4. 代表性期刊论文

  1. Chen B-S, de Souza FZR, (2019) Enzymatic synthesis of enantiopure alcohols: current state and perspectives. RSC Advances, 2019,9, 2102-2115 

  2. Chen B-S#, Médici R#, van der Helm MP, van Zwet Y, Gjonaj L, van Der Geest R, OttenLG,

    Hanefeld U (2018) Rhodococcus strains as source for ene-reductase activity. Applied Microbiology and Biotechnology,102:5545-5556.

  3. Liu H, de Souza FZR, Liu L*, Chen B-S*, (2018) Immobilized and free cells of Geotrichum candidum for asymmetric reduction of ketones: stability and recyclability. Molecules, 2018, 23: 2144-2168.

  4. Liu H,  Duan W-D, de Souza FZR, Liu L,Chen B-S*, (2018) Asymmetric Ketone Reductionby Immobilized Rhodotorula Mucilaginosa. Catalysts, 8, 165; doi:10.3390/catal8040165.

  5. Liu H,  Chen B-S*, de Souza FZR, Liu L (2018) A Comparative Study on Asymmetric Reduction of Ketones Using the Growing and Resting Cells of Marine-Derived Fungi. Marine Drugs 16:62.

  6. Liu H, de Souza FZR, Liu L, Chen B-S*, (2018) The use of marine-derived fungi for preparation of enantiomerically purealcohols. Applied Microbiology and Biotechnology 102:1317–1330 .

  7. Li F, Lin Z-F, Wen J-S, Wei Y-S, Gan H-Y, He H-J, Lin J-Q, Xia Z, Chen B-S*, Guo W-J, Tan C-S, Cai H-Y.   (2017). Risk assessment of trace metal-polluted coastal sediments on Hainan Island:
    A fullscale set of 474 geographical locations covering the entire island. Marine Pollution Bulletin,     125:541-555.

  8. Chen B-S, Liu H, deSouza FZR, Liu L (2017). Organic solvent-tolerant marine microorganisms as catalystsfor kinetic resolution of cyclic β-hydroxykKetones. Marine Biotechnology, 19:351-360.

  9. Chen B-S, Otten LG,Hanefeld U (2015) Stereochemistry of enzymatic water addition to C = C bonds,Biotechnology Advances 33: 526-546.

  10. Chen B-S, Resch V,Otten, LG, Hanefeld U (2015) Enantioselective Michael addition of water, Chemistry-AEuropean Journal 21: 3020-3030.

  11. Chen B-S,  Hanefeld U (2013) Enantioselective preparation of (R)- and(S)-3-hydroxycyclopentanone by kinetic resolution, Journal of MolecularCatalysis B: Enzymatic 85: 239-242.

  12. Chen B-S, Otten LG,Resch V,  Muyzer G, Hanefeld U (2013)Draft genome sequence of Rhodococcus rhodochrous ATCC 17895, Standards in GenomicSciences 9: 175-184.

  13. Chen B-S, Yang L-H, Ye J-L,Huang T, Ruan Y-P, Fu J, Huang P-Q (2011) Diastereoselective synthesis andbioactivity of long-chain anti-2-amino-3-alkanols, European Journal ofMedicinal Chemistry 46: 5480-5486.

  14. Chen B-S, Jin J, ReschV, Hanefeld U. Enantioselective Michael addition of water using Rhodococcus rhodochrousATCC 17895. In: Whittal J., Sutton P., Kroutil W.(eds), Practical Methods inBiocatalysis and Biotransformations, Wiley-VCH; 2016, Chapter 4, 106-112.

  15. ReschV, Seidler C, Chen B-S, Degeling C,Hanefeld U (2013) On the  Michaeladdition of water to α,β-unsaturated ketones using amino acids, EuropeanJournal of Organic Chemistry 7697-7704.

  16. ReschV, Jin J,  Chen B-S, Hanefeld U (2014) Michaelhydratase alcohol dehydrogenase or just alcohol dehydrogenase?  AMB Express, 4: 30-36.

5. 主持项目

  1. 高校基本科研业务费中山大学青年教师培育项目：15万，执行年限：2017.1-2019.12

  2. 广东省自然科学基金博士启动项目：10万，执行年限：2017.5-2020.4

  3. 国家自然科学基金青年基金项目：25 万，执行年限：2018.01-2020.12

 

 

6. 专利

1. 陈碧双，刘岚，刘慧，杨振男，白地霉菌株不对称催化还原卤代芳香酮的方法，2017，CN107418981A

2. 陈碧双，刘岚，刘慧，杨振男，一种烯键还原酶及其制备和应用，2017，CN106906226A.

3. 黄培强, 傅瑾 ( 第一第二作者为指导老师 ), 陈碧双, 杨隆河, 叶剑良,邻氨基醇类化合物及其制备方法与应用, 2011,  CN102241596A.