李浩洋
讲师/专任教员/助研/实验师/博后
单位:海洋生物养殖与环境研究所 行政职务:
学科专业:海洋生物学 专业技术资格/导师:博士后
办公电话: 手机:15018453671
电子邮箱:285624316@qq.com
通讯地址:广东省广州市番禺区大学城中山大学
 
 

研究方向

水生生物宿主免疫与病原关系

招生专业

海洋生物学

个人详细介绍

李浩洋,博士后,于20177月正式加入中山大学海洋科学学院,其合作导师是王江海教授。

20176月从中山大学获得水生生物学博士学位后,李浩洋博士进入何建国教授团队开展博士后工作。其研究方向是水生动物宿主免疫与病原的关系,目前重点开展的工作内容是无脊椎动物胞质DNA识别应答的抗病毒机制。

李浩洋博士博士攻读期间发表SCI论文20篇,其中以第一作者身份发表SCI论文4篇,以第二作者发表SCI论文6篇。这些研究都围绕着对虾先天免疫通路与以副溶血弧菌和白斑综合征病毒为代表的病原之间的关系展开,涵盖了多条免疫通路和不同的抗病原机制,为后续研究工作开展打下坚实的基础。以下为李浩洋博士博士攻读期间发表的SCI论文:

1. Haoyang Li1, Yonggui Chen1, Ming Li, Sheng Wang, Hongliang Zuo,Xiaopeng Xu, Shaoping Weng, Jianguo He*, Chaozheng Li*. AC-type lectin ( LvCTL4 ) from Litopenaeus vannamei, is a downstream molecule ofthe NF-κB signaling pathway and participates in antibacterial immuneresponse[J]. Fish & Shellfish Immunology, 2015, 43(1):257-63.

2.Haoyang Li, Sheng Wang, Zhe Qian,Zhenzhen Wu, Kai Lǚ, Shaoping Weng, Jianguo He*, Chaozheng Li*.MKK6 from pacific white shrimp Litopenaeus vannamei is responsive to bacterialand WSSV infection.[J]. Molecular Immunology, 2016, 70:72-83.

3. Haoyang Li, ShengWang, Kai Lǚ, Bin Yin, Bang Xiao, Sedong Li, Jianguo He*, ChaozhengLi*. An invertebrate STING from shrimp activates an innate immunedefense against bacterial infection[J]. FEBS Letters, 2017, 3.

4.HaoyangLi, Sheng Wang, Yonggui Chen, Kai Lǚ, Bin Yin, Sedong Li, Jianguo He*,Chaozheng Li*. Identification of two p53 isoforms fromLitopenaeus vannamei and their interaction with NF-κB to induce distinct immuneresponse. [J]. Scientific Reports, 2017, 7.  

5.Hongliang Zuo, Haoyang Li, ErmanWei, Ziqi Su, Jieyao Zheng, Chaozheng Li, Yonggui Chen, Shaoping Weng, JianguoHe*, Xiaopeng Xu*. Identification and functional analysisof a Hemolin like protein from Litopenaeus vannamei[J]. Fish & ShellfishImmunology, 2015, 43(1):51-9.

6. ShengWang, Haoyang Li, Zhen Qian, XuanSong, Zijian Zhang, Hongliang Zuo, Xiaopeng Xu, Shaoping Weng, Jianguo He*,Chaozheng Li*. Identification and functional characterization of theTAB2 gene from Litopenaeus vannamei[J]. Fish & Shellfish Immunology, 2015,46(2):206-16.

7. ChaozhengLi, Haoyang Li, Yixiao Chen, YongguiChen, Sheng Wang, Shaoping Weng, Xiaopeng Xu*, Jianguo He*.Activation of Vago by interferon regulatory factor (IRF) suggests an interferonsystem-like antiviral mechanism in shrimp[J]. Scientific Reports, 2015, 5.

8. ChaozhengLi*, Haoyang Li, ShengWang, Xuan Song, Zijian Zhang, Zhe Qian, Hongliang Zuo, Xiaopeng Xu, ShaopingWeng, Jianguo He*. The c-Fos and c-Jun from Litopenaeus vannamei,play opposite roles in Vibrio parahaemolyticus, and white spot syndrome virusinfection[J]. Developmental & Comparative Immunology, 2015, 52(1):26-36.

9. ShengWang, Haoyang Li, Kai Lǚ, Zhe Qian,Shaoping Weng, Jianguo He*, Chaozheng Li*. Identificationand characterization of transforming growth factor β-activated kinase 1 fromLitopenaeus vannamei, involved in anti-bacterial host defense[J]. Fish &Shellfish Immunology, 2016, 52:278-288.

10.Chaozheng Li*, Haoyang Li,Bang Xiao, Yonggui Chen, Sheng Wang, Kai Lǚ, Bin Yin, Sedong Li, Jianguo He*.Identification and functional analysis of a TEP gene from a crustacean revealsits transcriptional regulation mediated by NF-κB and JNK pathways and its broadprotective roles against multiple pathogens[J]. Developmental & ComparativeImmunology, 2017, 70:45.

11. Chaozheng Li, Jiaoting Chai, Haoyang Li, Hongliang Zuo, Sheng Wang,Wei Qiu, Shaoping Weng, Jianguo He*, Xiaopeng Xu*.Pellino protein from pacific white shrimp Litopenaeus vannamei, positivelyregulates NF-κB activation[J]. Developmental & Comparative Immunology,2014, 44(2):341-50.

12. ShengWang, Zhe Qian, Haoyang Li, Kai Lǚ,Xiaopeng Xu, Shaoping Weng,Chaozheng Li*, Jianguo He*.Identification and characterization of MKK7 as an upstream activator of JNK inLitopenaeus vannamei.[J]. Fish & Shellfish Immunology, 2015, 48:285-294.  

13. MingLi1, Chaozheng Li1, Chunxia Ma, Haoyang Li, Hongliang Zuo, Shaoping Weng, Xiaohan Chen, DigangZeng, Jianguo He*, Xiaopeng Xu*. Identification of aC-type lectin with antiviral and antibacterial activity from pacific whiteshrimp Litopenaeus vannamei.[J]. Developmental & Comparative Immunology,2014, 46(2):231-240.

14. Xuan Song1,Zijian Zhang1, Sheng Wang, HaoyangLi, Hongliang Zuo, Xiaopeng Xu, Shaoping Weng, Jianguo He*,Chaozheng Li*.A Janus Kinase in the JAK/STAT signaling pathway fromLitopenaeus vannamei, is involved in antiviral immune response[J]. Fish &Shellfish Immunology, 2015, 44(2):662-673.

15. Shuang Zhang, Lili Shi, Kai Lǚ, Haoyang Li, Sheng Wang, Jianguo He*,Chaozheng Li*. Cloning, identification and functional analysis of aβ-catenin homologue from Pacific white shrimp, Litopenaeus vannamei.[J]. Fish& Shellfish Immunology, 2016, 54:411-418.

16. Sheng Wang, Xuan Song, Zijian Zhang, Haoyang Li, Kai Lǚ, Bin Yin, Jianguo He*,Chaozheng Li*. Shrimp with knockdown of LvSOCS2, a negative feedbackloop regulator of JAK/STAT pathway in Litopenaeus vannamei, exhibit enhancedresistance against WSSV[J]. Developmental & Comparative Immunology, 2016,65:289–298.

17. Sheng Wang,Mengqiao Li, Bin Yin, Haoyang Li, BangXiao, Kai Lǚ, Zhijian Huang, Sedong Li, Jianguo He, Chaozheng Li.(2017). Shrimp tab1 interacts with tak1 and p38 and activates the host innateimmune response to bacterial infection. Molecular Immunology,2017, 88:10-19.

18. MutingYan, Junliang Tang, Qianhui Liang, Guohua Zhu, Haoyang Li, Chaozheng Li, Shaoping Weng, Jianguo He*,Xiaopeng Xu*. Identification of a JAK/STAT pathway receptor domelessfrom Pacific white shrimp Litopenaeus vannamei[J]. Fish & ShellfishImmunology, 2015, 44(1):26.

19. MutingYan1, Chaozheng Li1, Ziqi Su, Qianhui Liang, Haoyang Li, Shizhong Liang, ShaopingWeng, Jianguo He*, Xiaopeng Xu*. Daxx from Pacific whiteshrimp Litopenaeus vannamei is involved in activation of NF-κB pathway.[J].Fish & Shellfish Immunology, 2015, 45(2):443.

20. Chaozheng Li, Yixiao Chen, Shaoping Weng, Sedong Li, Hongliang Zuo,Xiaoqiang Yu, Haoyang Li, Jianguo He*,Xiaopeng Xu*. Presence of Tube isoforms in Litopenaeus vannameisuggests various regulatory patterns of signal transduction in invertebrateNF-κB pathway.[J]. Developmental & Comparative Immunology, 2014,42(2):174-185.